Unfortunately, these compounds showed non-specific inhibition of viable cell proliferation, based on their cytotoxic effects in DNAJA1 and/or mutp53 knockout cells; however, PLTFBH showed specific inhibition of filopodia formation and migration of cancer cells expressing conformational mutp53 with minimal impact on cells with wtp53, p53 null, and DNA contact mutp53. Here, TP53 is linked to cancer.