Tumour samples from patients with NLR values higher than 3.78 showed 12 genes differentially expressed (TYK2, RIPK2, TRAF2, IKBKB, DUSP6, PTGS2, CCND3, RUNX1, HSPA1A, ELK1, TFRC, and NFATC4, p-value < 0.05 and FDR < 0.05) versus patients with low NLR (Table 4). This evidence concerns the gene TYK2 and neoplasm.