INS and cancer: GO, KEGG and GSEA analysis of DE mRNAs, DE lncRNA-target genes, and DE miRNA target genes were significantly enriched in biological processes related to angiogenesis, EMT, mitotic cell cycle regulation, chromatin organization, metabolic pathways, and with cancer-related pathways, such as the PI3K-Ak signaling, TGF-beta signaling, p53 signaling, Insulin signaling, and HIF1 signaling pathways.