CSNK1A1 and Miyoshi myopathy: By exploiting three different co-culture models of MSC and MM cells, in which CK1α silencing was achieved in the MM compartment (model 1), in the MSC compartment (model 2) and in both cell populations (model 3), we were able to finely analyze the role of CK1α in the BM microenvironment and in PC–MSC cross-talk.