Using a univariate logistic regression, a high TROP2 expression was significantly correlated with a poor histological grade, mucinous and signet ring cell morphology, lymph node metastasis, an advanced stage III + IV, localization in the right colon, and positive staining for PD-L1 and CK7. The gene discussed is TACSTD2; the disease is metastatic malignant neoplasm in the lymph nodes.