ERBB2 and colorectal cancer: Here, we discuss the lessons learnt in establishing the following multi-disciplinary, multi-site national and international cancer registries—ACCORD (colorectal cancer) TRACC (advanced colorectal cancer), TABITHA (HER2 breast cancer), AURORA (ER breast cancer), PURPLE (pancreatic cancer), GATOR (gastro-oesophageal cancer), BRAIN (gliomas), ePAD (prostate cancer), KRAB (kidney cancer), BLADDA (bladder cancer), iTESTIS (testicular cancer), INHALE (lung cancer) and MASTER (melanoma) which partner with 82 cancer centres across Australia, New Zealand, Hong Kong and Singapore Figure 1.