In this paper, we analyzed the clinical and transcriptomic data available at the TCGA-LGG and CGGA databases, which collect samples of low-grade (grade 2) and anaplastic (grade 3) gliomas, and stratified the patients according to gender, tumor grade (2 or 3), and molecular features indicated in the WHO 2016 classification (IDH wild-type/mutated; 1p/19q codeleted/not). The gene discussed is IDH1; the disease is central nervous system cancer.