Our observation that chemerin treatment did not affect cellular migration or invasiveness of the ovarian cancer cell lines tested is in contrast to some in vitro studies, like on the mentioned HO8910 ovarian cancer cell line, on gastric cancer cells [58] or esophageal squamous cancer cells [59], but supports data indicating this adipokine to act in a tissue-specific and cell-line specific manner both in vitro and in vivo (reviewed in [15]). The gene discussed is RARRES2; the disease is ovarian cancer.