With regard to genes with decreased transcript levels 48 h after chemerin treatment, only POGZ gene, coding for the protein “Pogo transposable element with ZNF domain” was affected in all cell lines tested, whereas hormone-dependent OVCAR-3 and OAW-42 cells shared the highest number of down-regulated genes, including the tumor-promoting genes PTK2 and USP12 (Figure 5, right panel). Here, USP12 is linked to neoplasm.