With regard to non-tumorigenic ovarian tissue like in polycystic ovary syndrome (PCOS), a disorder linked to low-grade chronic inflammation, elevated blood levels of inflammatory cytokines and adipokines like chemerin were reported [26], and in these patients, a significant association between high intrafollicular androgen levels and chemerin [27] was reported. The gene discussed is RARRES2; the disease is polycystic ovary syndrome.