Meanwhile, no considerable difference was found in PFS or OS between these patients with Ki67 (Figure S3C,D), brain metastasis (Supplementary Figure S2E,F), chest wall metastasis (Supplementary Figure S4G,H), liver metastasis (Supplementary Figure S4I,J), lung metastasis (Supplementary Figure S4K,L), proteinuria (Supplementary Figure S5E,F), micropapillary (Supplementary Figure S6A,B) and vascular cancer embolus (Supplementary Figure S6C,D) with those who did not. This evidence concerns the gene MKI67 and vascular cancer.