Thus, significantly decreased expression of SALL4 and SRPX2 genes was detected in larger (>4 cm) tumours (p = 0.03; p = 0.02, respectively), while the overexpression of MYLK was more frequent in patients with tumours in the rectum (p = 0.003), at advanced stages (p = 0.01; pT3–pT4), and for which metastatic lymph nodes were present (p = 0.05; pN1–pN2). This evidence concerns the gene SALL4 and neoplasm.