To date, 43 cases of BRPF1 mutations reported confirm that BRPF1 is a causal gene for intellectual disability (ID) in a disease known as intellectual developmental disorder with dysmorphic facies and ptosis (IDDDFP) (12 cases [13], 10 cases [106], 12 cases [107], 1 case [108], 1 case [109], 1 case [110], 4 cases [111], 1 case [112], 1 case with schizophrenia and mild ID [113]). The gene discussed is BRPF1; the disease is schizophrenia.