POR and congenital adrenal hyperplasia due to cytochrome P450 oxidoreductase deficiency: Mutations in POR can lead to Cytochrome P450 oxidoreductase deficiency (PORD; OMIM 613,571 and 201750), a rare form of congenital adrenal hyperplasia, disrupting the steroid production in the adrenal and gonads [2,9].