(1) α-synTotal decreased significantly in PD, compared to CTR (p-value = 0.05); (2) α-synOligo, lactoferrin, and CCL2 increased significantly in PD, compared to CTR (respectively: p = 0.005; p = 0.002; p = 0.003); (3) Level of changes analyzed parameters were associated with sex; (4) AUROC test for α-synOligo was 0.80 and for α-synOligo and CLL2 was 0.83. This evidence concerns the gene LTF and Parkinson disease.