With the application of PC-3 PCa cell lines characterized by GRPR expression but androgen receptor (AR) and prostate specific membrane antigen (PSMA) deficiency, Schroeder et al. reported the superiority of 68Ga-AMBA over 18F-fluorocholine (18F-FCH) regarding the in-vivo PET imaging of PCa xenografts [16]. This evidence concerns the gene GRPR and posterior cortical atrophy.