BCL2 and leukemia: It was only natural to hypothesize that their respective triazole ester derivatives will act in a similar manner given the fact that the previously mentioned 28{1N (4-fluoro phenyl)-1H-1,2,3-triazol-4-yl} methyloxy betulinic ester clearly decreased Bcl-2/Bax ratio and activated caspase-9, thus inducing intrinsic apoptosis in HL-60 leukemia cells [26].