LGALS1 and neoplasm: Additionally, CathL contributes to angiogenesis by increasing expression of galectin 1 (Gal1) mRNA, leading to downstream activation of the MEK/ERK1/2 pathways, verified with immunohistochemistry of omental metastasis demonstrating a positive correlation between Gal1 and vascular proliferation [106].These results have been validated in murine models in which knockdown of CathL resulted in reduced tumor development [107].