AKT1 and brain neoplasm: Recently, a study reported the generation of a zebrafish transgenic line using a Tol2/LexPR transcription activator system that expresses human AKT1 under a neural-specific beta tubulin (NBT) promoter, which induced brain tumours with increased microglia population in neural cells mediated by Sdf1b-Cxcr4b signalling.