For example, Tg(fli1:GFP) zebrafish line with GFP-labelled vasculature, in particular, helps in understanding the mechanisms of neovascularisation, a crucial step in the tumour progression process that supports the growing tumour, as well as allowing therapeutic testing of antiangiogenic agents to inhibit tumour neovascularisation and thereby prevent tumour progression [67,135,136,137,138,211]. This evidence concerns the gene FLI1 and neoplasm.