We observed decreases in Plscr4 expression of 67.7% ± 15.4% in lipoma Pten/Rb DKO tissue compared with epiWAT (n = 7; p = 0.0019) and of 58.4% ± 23.5% compared with ingWAT (n = 7; p = 0.0318) (Figure 3a). This evidence concerns the gene RB1 and lipoma.