Using IHC staining, we confirmed the increase in the expression levels of p-Akt, p53, Bax, cleaved caspase-9 and -3, and PARP in the tumor tissues derived from MKN1 cell-implanted xenograft mice that were orally administered a mixture of B. bifidum MG731, L. reuteri MG5346, L. rhamnosus MG5200, or a mixture of B. bifidum MG731, L. reuteri MG5346, and L. rhamnosus MG5200 compared with the others (Figure 6). Here, TP53 is linked to neoplasm.