HSPB2 and breast carcinoma: In line with our findings, a recent comprehensive transcriptomic study of the HSP gene family in BrCa patients from both The Cancer Genome Atlas (TCGA) and the Molecular Taxonomy of Breast Cancer International Consortium (METABRIC) cohorts revealed that HSPB2 gene expression levels are profoundly downregulated in all BrCa molecular subtypes as compared to normal breast tissues [46].