Specifically, SARS-CoV-2-mediated deregulation of Rab7a and nucleoporin-62 (NUP62) could be strongly involved in PD pathogenesis, because Rab7 lysosomal protein decreases α-syn aggregation and associated neurotoxicity [164], while NUP62 is crucial for autophagosome development [165]. Here, RAB7A is linked to Parkinson disease.