CXCL8 and COVID-19: Considering that sHLA-G levels were increased in COVID-19 patients, irrespective of disease severity, the increased sHLA-G levels occurred together with the currently reported inflammatory IL-6, IL-8, and IL-10 cytokines, and positive correlations were observed between sHLA-G and these cytokines; only IL-10 has a well-recognized role on the induction of the HLA-G gene expression [50].