A recent study [34] demonstrated that SARS-CoV-2 replication is reduced in bronchial cells from people with cystic fibrosis (pwCF), a lethal genetic disease with autosomal recessive inheritance caused by mutations in the CFTR gene [35], which codes for the CFTR membrane protein, an ion channel involved in both chloride and bicarbonate ion transport [36,37,38,39]. The gene discussed is CFTR; the disease is cystic fibrosis.