To further evaluate whether the reciprocal mTOR/miR-99b-5p pairing can also serve as a potential biomarker for solid tumors in general, IHC, Western blot, and RT-qPCR assays were performed to examine the expression levels of the mTOR protein and miR-99b-5p in colon, breast, and lung cancers. This evidence concerns the gene MTOR and lung carcinoma.