The immunofluorescence assays have revealed higher levels of cytoplasmic mTOR vs. nuclear mTOR in 22Rv1, LNCaP, and PC-3 cells, whereas nearly equal distribution of cytoplasmic and nuclear mTOR were observed in RC77 T/E and MDA PCa 2b (green fluorescent mTOR signals and DAPI signals in Figure 2A). The gene discussed is MTOR; the disease is posterior cortical atrophy.