The CCL20-CCR6 axis functions in regulating the cutaneous immune response by driving the migration of different kinds of inflammatory cells, including B cells, immature dendritic cells, innate lymphocytes (ILC), regulatory CD4 T cells, and Th17 cells, and activation of the CCL20-CCR6 axis has been observed in psoriasis [94]. This evidence concerns the gene CCL20 and psoriasis.