MW Lingen et al. also revealed that transcription of NOL7 was positively regulated by the RB tumor suppressor in cervical cancer and that it further functioned as an mRNA-binding protein to modulate TSP-1 expression by enhancing the post-transcriptional stability of its mRNA, thus inducing an anti-angiogenic and tumor-suppressive phenotype [8,9]. Here, RB1 is linked to neoplasm.