ITGB2 and periodontal disorder: When controlling/adjusting for the covariates; OM status, viral load, sex, smoking status, alcohol intake, periodontal disease staging, medications affecting oPMNs and treatment modality, there were statistically significant fold-change decreases in the levels of CD11b, CD16, CD18, CD64 and H3Cit at the same time points as discussed for the above (Figure 3).