When controlling/adjusting for the covariates; OM status, viral load, sex, smoking status, alcohol intake, periodontal disease staging, medications affecting oPMNs and treatment modality, there were statistically significant fold-change decreases in the levels of CD11b, CD16, CD18, CD64 and H3Cit at the same time points as discussed for the above (Figure 3). Here, ITGB2 is linked to ocular melanoma.