TRPV1 and colitis: We have planned for in-vivo follow-up studies in the mouse model of IBD (colitis) (using global and tissue-specific TRPA1 and TRPV1 knock out animals or TRPA1/V1 double knock out and, TRPA1/TRPV1 silencing approach in primary cells) to establish an exact role of neuronal nociceptive TRPA1 and TRPV1 channels in colonic mucosal alterations, especially in IBD conditions.