MG1363-pMG36e-GLP-1 is beneficial for relieving inflammation in PD mice since it reduces TLR-4 expression, down-regulates p-NF-κB in the NF-κB signaling pathway and reduces the expression of proinflammatory factors IL-1β, IL-6, and TNF-α at both the gene and protein levels. This evidence concerns the gene GCG and Parkinson disease.