In patients with RA and controls with self-reported periodontitis, we found significant associations between two SNPs in PADI2 (rs2057094 and rs2235912) and RA after adjustment for age, sex, and smoking status (Odds Ratio (OR) 1.42 [p = 0.03] and 1.48 [p = 0.02], respectively) (Table 2); rs2076616 showed a similar trend (OR 1.35, p = 0.08). Here, PADI2 is linked to rheumatoid arthritis.