Results showed overexpression of two genes coding for lysyl hydroxylases, procollagen-lysine, and 2-oxoglutarate 5-dioxygenase (PLOD) [66], PLOD1, and PLOD2, involved in collagen biosynthesis and crosslinking [66,67] in LGG-IDH1wt and GBM. Here, PLOD1 is linked to glioblastoma.