Allicin caused inhibition of cellular growth in a concentration- and time-dependent manner.DNA fragmentation and morphological changes (degeneration of neuritis, shrinkage of cell bodies and condensation of nuclei) in cells exposed to 5–20 μg/mL for 24 h.45.2% apoptotic cells.↑ in the sub-G1 DNA content.↓ in the proportion in cells of S phase after exposure to 20 μg/mL of allicin for 24 h.Allicin results in the release of Cyt c and in increase of mitochondrial Bax protein level. Caspase-3 activation and cleavage of PARP were not detected. The gene discussed is BAX; the disease is neuritis.