0–10 μM caused ˂20% CRC cell deaths.DADS + TRAIL produced concentration-dependent decreased of % survival in SW620 cells, but not in FHC cells.0–10 μM did not alter the expression of pro-apoptotic proteins (Bax and Bid) or antiapoptotic proteins (XIAP and olorecta) and Bcl-2 were down-regulated in CRC cell lines. The gene discussed is XIAP; the disease is colorectal carcinoma.