The results of pathway enrichment analysis showed that compared with hADSCs in the basic state, the DEGs produced after IFN-γ, KYNA, and hADSCs co-culture were mainly enriched in signals related to antigen processing and presentation, cell adhesion molecule pathways, cytokine and receptor interaction, Th1, Th2, and Th17 cell differentiation, IBD, IFN-γ signaling pathways, TNF signaling, and anti-viral infection signals in the pathway. This evidence concerns the gene TNF and inflammatory bowel disease.