BRF1 and Abnormality of the dentition: But it is not understandable why some genetics, such as the BRF1 gene, are not considered and categorized as one of the PCH genes because PCH type 3 in addition to pontocerebellar hypoplasia they express some facial dysmorphism and dental anomaly and other types of PCH as type 7 could express other problems as disorder of sex develeopment in males.