Full concordance in representative mutated genes, including KMT2D, LRP1B, NAV3, TP53, FAT1, MKI67 and PKHD1L1, was observed in original cervical cancer, F2-PDX models and F3-PDX models, which were also identified as frequently mutated genes in cervical cancer samples in the TCGA database. This evidence concerns the gene KMT2D and cervical cancer.