When patients were categorized by age, serum high-density lipoprotein-cholesterol (HDL-C) and adiponectin levels significantly increased, whereas BW, body mass index (BMI), percent body fat, immunoreactive insulin (IRI), the insulin resistance index (HOMA-R), insulin secretion index (HOMA-β), serum leptin and alanine aminotransferase (ALT) levels, and the platelet count significantly decreased in an age-dependent manner. This evidence concerns the gene LEP and Insulin resistance.