SOAT1 and myeloproliferative disorder: We observed rs7851556 in 9p24.1 as the most significant variant (odds ratio (OR) = 2.39, 95% confidence interval (CI) = 2.13–2.68, P = 5.75 × 10−51), which is in strong linkage disequilibrium (LD) with the lead variant reported for MPN, rs1327494 (R2EUR = 0.95, D′EUR = 0.98)20 and located in an intron of JAK2, a gene which promotes cellular proliferation through the JAK/STAT pathway8,24.