Finally, we generated primary blood monocyte-derived DCs (mDCs) from human donors genotyped for the IFITM3 SNP rs12252 and stimulated cells with HCMV, with these cells being non-permissive to HCMV infection similarly to iPS-DCs (Supplementary Fig. 3c). The gene discussed is IFITM3; the disease is cytomegalovirus infection.