EGF and hepatocellular carcinoma: In the last decades, the complex relationship between platelets and hepatocellular carcinoma (HCC) has been largely studied, both in vitro and in vivo, with results showing that platelets can be considered a central player in liver regeneration and hepatocarcinogenesis, with several platelet‐related factors such as serotonin, platelet‐derived growth factor (PDGF),epidermal growth factor (EGF) and vascular endothelial growth factor (VEGF) variously acting in the angiogenic, inflammatory and proliferative processes.1, 2