Twenty CCI-based interactions, Sema6d-Plxna1, Nrxn1/2/3-Nlgn1/2/3, Ncam1-Ncam1/2, Ncam1-L1cam, Ncam1-Fgfr1, Lrrc4b-Ptprf, Jam2-Jam2/3, Jam2-F11r, Jam2-(Itgav+Itgb1), and App-Cd74, were weaker in SMA. The gene discussed is APP; the disease is proximal spinal muscular atrophy.