H19 and cancer: Noncoding RNA H19 is highly expressed in various cancers.17 For instance, miR-675-5p, a micro-RNA from H19, can bind to some specific mRNA-encoding proteins, thus inhibiting its expression.18 E-cadherin is closely related to cell adhesion and contact inhibition.19 The abnormal expression of E-cadherin in cancers may promote cancer metastasis.20 E-cadherin expression is decreased in oral cancers.21 Therefore, the irregular expression of E-cadherin can be used as a biomarker for clinical diagnosis, treatment, and prognosis of tumors,22 indicating that H19/miR-675-5p and CDH1 may be related.23