Moreover, the strong absorption in the second near‐infrared biowindow (NIR‐II, 950−1350 nm) enabled the CuS5 with excellent photothermal performance and generated substantial heat in deep tumor tissues.[48] 1‐MT released from PRNsMT effectively inhibited IDO activity and alleviated immunometabolic disorders, which in turn sensitized the PICT. Here, IDO1 is linked to neoplasm.