To determine which IFN receptor promotes lung disease in SAVI mice, we histologically evaluated the lungs of age- and sex-matched SAVI mice, including SAVI mice lacking 1 of the 3 IFN receptors: IFNAR1, IFNGR1, or IFNλR1 (Figure 1, A and B, and Supplemental Figure 1A; supplemental material available online with this article; https://doi.org/10.1172/jci.insight.155250DS1). Here, IFNAR1 is linked to lung disorder.