EGFL7 and neoplasm: EGFL7 may be involved in the following two aspects of the process of tumor metastasis: (1) EGFL7 protein stimulates the movement and migration ability of tumor cells by autocrine or paracrine and participates in the invasion and metastasis of tumor from the primary site to the surrounding areas; (2) EGFL7 protein secreted by tumor endothelial cells facilitates the infiltration of tumor cells into the bloodstream from the primary site, leading to the formation of tumor organ-specific metastases.