On the one hand, Spearman correlation analysis revealed that SOX17 expression in the ESCC was negatively correlated with Cyclin D1 expression (rs = −0.451), VE-cadherin expression (rs = −0.487), and VM (rs = −0.609, all P < 0.001; Table 2). Here, CDH5 is linked to esophageal squamous cell carcinoma.