CRP and bacterial infectious disease: The ROC curve analysis for predicting culture-proven bacterial infection with or without bacteremia yielded an AUC value 0.596 (95% CI: 0.551–0.641) for presepsin, 0.665 (95% CI: 0.621–0.709) for PCT, and 0.581 (95% CI: 0.550–0.642) for CRP (Figure 1A).