CDC42 and nonpapillary renal cell carcinoma: Wang et al. demonstrated that circHIAT1 functions in ccRCC development through miR-195-5p/29a-3p/29c-3p/CDC42 signalling [17], while Xue et al. elucidated that circ-AKT3 suppresses ccRCC progression by altering the miR-296-3p/E-cadherin pathway [18].