PRF1 and nonpapillary renal cell carcinoma: The calcein release assay (Figures 5(i)–5(l)), perforin polarization assay (Figures 5(m)–5(p)), and conjugation assay (Figures 5(q)–5(t)) indicated that the promotive effect of circFOXO3 overexpression on ACHN or Caki-1 cell death was rescued by miR-122-5p or miR-29a-3p overexpression, partially verifying the biological function of circFOXO3/miR-122-5p/miR-29a-3p in ccRCC development.