In addition, in normal tissue, HNSC and TCGA RNA sequencing data showed through GEPIA2 and UALCAN analysis that expression of DEPDC1 is upregulated in tumour tissues compared to normal tissue (Supplementary Figures 1B, D), whereas stages were significantly associated with DEPC1 expression (Supplementary Figure 1C). This evidence concerns the gene ALKBH3 and neoplasm.