The HBG2 encodes the hemoglobin subunit gamma-2 protein, the predominant type of hemoglobin in the fetus, which is responsible for oxygen transport within the circulation, so the disorder of this gene would result in fetal hematological abnormalities (e.g., anemia, cyanosis, hypoxia) (92). The gene discussed is HBG2; the disease is Abnormality of the skin.