While we have not investigated the timing of active TGFβ delivery by MLN cDC1 to B cells during rotavirus infection (124), we propose that cDC, migrating from the lamina propria to the MLN, could present activated-TGFβ to B cells concomitantly with the presentation of native antigen coated on their surface, as previously demonstrated (133, 134). The gene discussed is TGFB1; the disease is Rotavirus infection.